Introduction: In this study, it was aimed to examine the relationship between procalcitonin (PCT) values and complications, age, mortality, survival and to evaluate the correlation of procalcitonin, C-reactive protein (CRP), and white blood cell (WBC) values in patients operated for gastric cancer. Methods: File records of 50 patients who were operated on for gastric cancer between 2015 and 2018 and whose procalcitonin levels were obtained were retrospectively reviewed. Results: Eighteen (36%) of the study participants in the study were female, and 32 (64%) were male. Mortality rates were found to be significantly higher in those with PCT values of 2 and above on PO 1st and 3rd days. It was observed that the development of respiratory complications was significantly higher in patients with a PCT value of 2 and above on PO 5th and 7th days. Conclusions: Post-operative high values in gastric cancer patients are significant in terms of mortality and survival in the follow-up. In gastric cancer and other malignant diseases, it is necessary to determine cut-off values, to conduct specificity and sensitivity studies by making detailed examinations for respiratory complications, mortality, and survival times during treatment.
Background: Rectal cancer ranks 3rd among the most common malignancies in both sexes. Abdominal infections that can be seen after rectal cancer surgery are the most feared postoperative complications, as they can also be the harbinger of anastomotic leakage. According to its localization, the rate of anastomotic leak varies between 4% and 29.5%. Procalcitonin (PCT) is an increasing parameter in bacterial infections and sepsis. Therefore, it is used to monitor the infection and the effectiveness of the treatment. Our study we aimed to evaluate the effect of PCT on early diagnosis of anastomotic leakage in rectal surgery and the correlation between PCT and CRP and WBC levels.Methods: File records of 50 patients who were operated on for rectal cancer and had anastomosis between 2016 and 2019 were retrospectively analyzed. Demographic features, operation information, preoperative and postoperative clinical features of the patients were recorded. The WBC, CRP and procalcitonin values of the patients were measured on the preoperative and postoperative 1st and 5th days. Patients were divided into two groups as PC values<2 ng/ml and ≥2 ng/ml. Patients with surgical site infections were found. The relationship between hospital stay and PCT levels and those with surgical incision site infection and those with intra-abdominal infection was examined. The correlation between PCT values and CRP and WBC values of the patients was evaluated.Results: There was no significant difference in PCT values in infections at the surgical incision site. However, it was observed that the PCT values of patients with surgical infection in the abdomen were significantly higher than those without (p=0.005). It was observed that the PCT level was high and the duration of hospital stay was observed to be prolonged in patients with infections in the surgical incision area and in the abdomen.Conclusions: PCT can be used as a biochemical parameter in terms of abdominal infection and anastomotic leaks. It is recommended to be checked especially on the fifth postoperative day and to investigate for anastomotic leakage if it is seen to reach the highest value.
Aim Pancreatic cancer is one of the deadliest malignant neoplasms. As with many malignant neoplasms, survival rates depend on the histopathological type of cancer, its stage, tumor size, and treatment. In this study, we aimed to classify pancreatic cancer according to clinicopathological features and histological subtypes. Material and method The data of all adult patients diagnosed and treated for pancreatic neoplasm in our clinic were collected retrospectively from the hospital's computerized database and medical files. Patients were categorized according to their clinicopathological features. Chi-square test and Fisher's exact test were used for between-group comparisons, and t-test was used for independent samples for quantitative data. Data were expressed as mean ± SD for continuous variables and numbers and percentages for categorical variables. A value of p<0.05 was considered significant. Results The mean age of the patients was 60.5 years, 70.8% were male. There were five types of tumors defined histopathologically, and the most common diagnosis was adenocarcinoma (76.9%). The most common localization of the tumor was head and neck (44.4%). Whipple surgery was performed predominantly in 69.2% of patients, and distal pancreatectomy in 29.0%. Postoperative complications were observed in more than one third (34%) of the patients. The main complications were pancreatic cyst (16.3%). In the survival analysis performed with the Kaplan-Meier test, median survival of 30.5 months, and overall survival (OS) at 1.2 and 5 years were 67.8%, 40.5%, and 16.6%, respectively. Discussion However, survival analysis results were optimistic compared to population-based studies as all patients had resectable tumors.
Objectives: This study aimed to discuss the frequency of early readmission to the hospital after discharge in our oncology clinic, clinicopathological features, and management of these patients in light of current literature. Methods: The medical records of 237 early readmitted patients within 30 days of discharge in our clinic were retrospectively reviewed. The patients were categorized according to their first diagnosis, Eastern Cooperative Oncology Group (ECOG) performance status, demographic, clinicopathological characteristics, readmission reasons, first treatment type, postoperative complications, the time of application after discharge and the type of treatment after admission.Results: The mean age of the patients was 58.45 years, 57.4% were female, and the mean readmission time after discharge was 11.54 days. The most common primary diagnosis was gastric cancer (35.9%), and the most common emergency pathology requiring hospitalization was ileus-subileus (45.1%). After readmission, 42.6% of the patients received medical treatment. 60% of the readmitted patients had postoperative complications before discharge. Patients who had postoperative complications during the first hospitalization were more likely to have major or minor interventions after readmission (p < 0.01). Admission with a diagnosis of bowel obstruction was associated with the probability of major intervention (p < 0.01). Patients with an ECOG performance score of ≥2 was more frequently administered medical treatment (p = 0.001). Patients admitted with the diagnosis of anastomotic leak/abscess had a higher probability of having postoperative complications (p = 0.001). Conclusions: Readmissions are a concern for all healthcare providers, including comprehensive cancer centers. Recent health policies strive to reduce preventable admissions. Hence, we believe focusing on postoperative complications, and palliative care services is necessary.
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