The treatment with fractionated CO2 laser appeared to be a feasible and effective treatment for VVA dyspareunia in breast cancer survivors with contraindications to hormonal treatments.

Long-term data showed that the improvement of vaginal health may continue up to 24 months after fractional CO laser treatment although between 18 and 24 months benefits decline, and approximately 80% of women decide to start a new treatment cycle of laser applications.

The presence of uterine myomas during pregnancy is considered a risk factor for gestation and delivery. In literature, myomas are related to spontaneous abortion, bleeding, PPROM, preterm delivery, placenta previa, placental abruption, fetal malpresentations, mechanical dystocia and high incidence of cesarean section. Laparotomic myomectomy done during pregnancy is indicated when symptoms related to uterine myomas, as acute pelvic pain or gastroenteric or urinary symptoms, persist despite the pharmacological therapy. The purpose of this study is to show a successful surgical management of uterine myomas at 15.5 weeks of pregnancy, which allowed the continuation of gestation and a delivery without major complications.

and here we describe what appears to be only the 12th such case of a pregnant woman who suff ered this. Immediately aft er being diagnosed with agranulocytosis, the patient was given emergency treatment involving the cessation of ritodrine therapy, intramuscular injections of G-CSF and antibiotics to prevent infection. Both the patient and her twin fetuses showed good prognosis. A review of the literature supports the effi cacy of this treatment approach. Previous cases and ours suggest that ritodrine should be used carefully for avoiding premature labour, and that white blood cell counts and temperature should be monitored regularly in pregnant women receiving this drug.