Purpose: The purpose of this article is to study the main domestic and foreign politics defining national priorities of the Border Policy of the Republic of Kazakhstan under conditions of sovereignty. Methodology: Scientific-theoretical base and methodologies of foreign and domestic border studies are an object of research. Features of existing modern international approaches in the research of Border Policy issues are considered. Main Findings: Specifics of domestic border studies formation and its theoretical-methodological base were analyzed, on the basis of the works of the Kazakhstan Scientists publicly available. Theoretical-methodological bases of domestic border studies were defined. Applications: The study may be used for further determination of the national priorities of the border policy of the Republic of Kazakhstan and for the close study of new paradigms in border policy tendencies under conditions of sovereignty. Novelty/Originality: The study generalizes the most feature streams and modern perspective tendencies of the border policy of the Republic of Kazakhstan what has never been done before in the selected points of view and by involving listed methodology.