The aim of the study was to show principles of diagnosis and treatment of Askin’s tumor in children. Diagnostic procedures include physical examination, chest X-ray, CT scan and PET CT, morphological, histological and immunohistochemical examinations, cytogenetic study. Primitive neuroectodermal tumors belong to the group of low differentiated, overly aggressive neoplasms, originating from cells of the parasympathetic autonomic nervous system. Patient F., 9 years old, first consulted by pediatric oncologist in 2014 with complaints of volume formation in the chest on the right side which progressively increases. Diagnosis: PNEP (primitive neuroectodermal tumor) of the soft tissues of the chest on the right side in the 4th intercostal space along the midclavicular line T2aN0M0, stage 2a, standard risk group. We’ve shown results of diagnostical process, treatment and it’s result in our patient. Patients who have received combination therapy, including chemotherapy, surgical removal of the tumor and radiation therapy, have better prognostic results. However, relapses often occur that require more aggressive treatment with high-dose chemotherapy, monoclonal antibodies, and bone marrow transplantation.

The article presents data on the causes of the formation of various types of bezoars in children, traces the causes of their complicated course in the form of bezoar disease. Modern issues of diagnostics, methods of treatment and formation of foreign bodies of the digestive tract in children are covered in the article. A clinical case of a giant trichobezoar of the stomach and duodenum in a 14-year-old girl is presented and analyzed. in a histological examination of the gastric wall.