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Highlights The precarious immigrant population is often invisible because it is at the interstices of care devices and, in the current epidemic context, isolation facilities. Confinement affects individuals' abilities to act, and generates a "disaffiliation process" to placing this precarious immigrant population even more on the margins of society. Covid-19 crisis exacerbates pre-existing difficulties, generating not so new situations for these precarious immigrant population. Need to formulate specifics interventions : targeted outreach intervention, participatory approach and deliberative spaces ; promote health promotion intervention; right based intervention.