The article presents a general description of the lymphatic system and detailed characteristics of the structure of the terminal thoracic duct (TD) and lymphovenous junction (LVJ): their clinical and anatomical features, the role of LVJ in regulating lymph flow, and the separating two systems (circulatory and lymphatic). The presented data expand the concept of the structural and functional characteristics of the left central LVJ, its valves, and TD, and also provides information about the anatomical heterogeneity of the studied tissue complex. The morphological and functional characteristics of LVJ will help to better understand the logistics of the lymph flow and the mechanism of the LVJ valves’ work. Keywords: Lymphatic system, thoracic duct, lymphovenous junction, ostial valve.