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COVID-19 disease has been identified to cause remarkable increase of mucormycosis infection cases in India, with the majority of cases being observed in individuals recovering from COVID-19. Mucormycosis has emanated as an outcome of the recent COVID-19 pandemic outbreak as rapidly developing fatal illness which was acquired by Mucorales fungus which is a subcategory of molds known as mucormycetes. Mucormycosis is one of the serious, sporadic mycotic illnesses which is a great threat to immunocompromised COVID-19 patients and affects people of all ages, including children with COVID-19 infections. This is associated with tissue damaging property and, therefore, causes serious clinical complications and elevated death rate. The COVID-19-associated mucormycosis or “black fungus” are the terms used interchangeably. The rapid growth of tissue necrosis presenting as “rhino-orbital-cerebral, pulmonary, cutaneous, gastrointestinal, and disseminated disease” are various clinical forms of mucormycosis. The patient’s prognosis and survival can be improved with proper surgeries using an endoscopic approach for local tissue protection in conjunction with course of appropriate conventional antifungal drug like Amphotericin-B and novel drugs like Rezafungin, encochleated Amphotericin B, Orolofim, and SCY-078 which have been explored in last few years. This review provides an overview of mucormycosis including its epidemiology, pathophysiology, risk factors, its clinical forms, and therapeutic approaches for disease management like antifungal therapy, surgical debridement, and iron chelators. The published patents and ongoing clinical trials related to mucormycosis have also been mentioned in this review. Graphical abstract

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Dendrimers, type of revolutionary nanomolecules, have gained a lot of popularity in recent years. These compounds can be developed and transformed in a variety of ways to produce a molecule that fulfills the requirements. As a result, dendrimers are the subject of extensive research in a variety of nanoscience domains, including one of the most promising biomedicine. Dendrimers are polymeric nanoparticles offering a huge number of benefits in biomedicine because of their nanometric dimensions, biocompatibility, multivalency, and structural perfection. In this review, we provide an overview of dendrimers, and the several types of dendrimers available, and their applications in the treatment of viral infections, as well as briefly summarize the recent patents on dendrimers used in viral infections. Dendrimer use is expected to be a game changer in the treatment and prevention of infectious diseases that continue to plague humanity, and it has the potential to dramatically improve the quality of people's lives.