In Hispaniolan Amazon parrots, oral administration of voriconazole was associated with proportional kinetics following administration of single doses and a decrease in plasma concentration following administration of multiple doses. Oral administration of 18 mg of voriconazole/kg every 8 hours would require adjustment to maintain therapeutic concentrations during long-term treatment. Safety and efficacy of voriconazole treatment in this species require further investigation.
Abstract. Spinal lymphoma and concurrent pulmonary filariasis are reported in a pet rabbit. The rabbit presented for pelvic limb paralysis resulting from extradural spinal lymphoma, presumably rising from the body of the sixth lumbar vertebra. The neoplasm was subsequently immunophenotyped as a B-cell lymphoma. Pulmonary filariasis was an incidental finding at necropsy.
A dog presenting with weight loss and displacement of the heart to the right was diagnosed as having a thymoma by transthoracic fine‐needle aspiration biopsy. The cytological findings are described and correlated with the histological findings. Cytologically the lesion contained numerous large clusters of neoplastic epithelial cells with scant basophilic cytoplasm, and scattered, well‐differentiated lymphocytes. Histologically the thymoma was composed of predominantly spindle‐shaped epithelial cells arranged in broad sheets or forming sworling and storiform patterns. Some lobules contained lymphoid cells.
Nathalie Radem acher1, DVM, DECVD, Shannon Shaw1, DVM 1. L ouisiana State U niversity School o f V eterinary M edicine, V eterinary Clinical Sciences, Skip B ertm an D r., B aton R ouge, LA 70803, U SAA bstr a c t: A 12-year-old, 15.4-kg, captive-born, m ale A frican spurred tortoise, Geochelone sulcata, was presented for separation o f the carapacial scutes. A C T scan was perform ed to determ ine the extent o f dam age to the carapace and to assess the integrity o f the tissue beneath it. T he scan revealed necrotic bone tissue consistent w ith sequestrum form ation, as well as areas o f possible com m unication w ith the coelomic cavity. Based on the scan results, it was decided to carry ou t conservative therapy followed by surgery to rem ove the sequestrum . T he sequestrum was successfully rem oved surgically, and the defect was repaired w ith the application o f dental acrylic and epoxy. This report illustrates the usefulness o f C T scanning in the diagnosis o f carapacial sequestra in chelonians. K ey W o r d s: A frican spurred tortoise, Geochelone sulcata, sequestrum , therm al injury, carapace. C a s e R e p o r t O n day 1, a 12-year-old, 15.4-kg, captive-born, m ale A frican spurred tortoise, Geochelone sulcata, was presented for evaluation o f separated carapacial scutes. T he tortoise h ad a history o f carapacial pyram iding, as well as problem s w ith an overgrow n pygal bone plate an d supracaudal scute. The pygal bone plate h ad been previously surgically reshaped to enable norm al defecation and m ovem ent o f the tail. A dditionally, oxyurid parasites had been diagnosed and treated. A t the tim e o f presentation, the tortoise was housed in an o u td o o r fenced yard in south Louisiana. Supplem ental h eat and ultraviolet-B (UVB) lam ps were provided during the w inter, and the diet consisted o f assorted fresh fruits and vegetables w ithout calcium supplem entation. P rio r to residence w ith its current owner, the tortoise was housed indoors w ithout exposure to UVB light. T he heat source consisted o f a house heat radiator. Its diet consisted o f an assortm ent o f fruits an d vegetables w ithout calcium supplem entation. R eportedly, the tortoise had a h ab it o f frequently leaning against the heat radiator. Physical exam ination o f the carapace revealed partial detachm ent o f the first vertebral, first left pleural, first left m arginal, and second left m arginal scutes. The scutes were only partially attached to the corresponding bony plates; a hollow sound was elicited upon percussion o f the scutes w ith a b lunt m etal object (a pair o f scissors). Blood was collected from the brachial plexus, b u t only enough blood was obtained for a chem istry profile because o f the uncooperative n atu re o f the patient. N o abnorm alities were observed in the blood chem istry profile. A solution o f clorhexidine (Nolvasan® Solution 2%, F o rt D odge A nim al H ealth, F o rt D odge, Iowa) and w ater at a 1:50 ratio was used to flush the spaces between the scutes and the derm al bone. Piece...
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