Aim To evaluate the theme trends and knowledge structure of multifetal pregnancy reduction (MPR)‐related literature by using bibliometric analysis. Methods Published scientific papers regarding MPR were retrieved from the PubMed database. Data extraction and statistics were conducted using Bibliographic Item Co‐Occurrence Matrix Builder (BICOMB). Furthermore, gCLUTO software was used in the study for bi‐clustering analysis and strategic diagram analysis. Results According to the search strategy, 906 total papers were included. Among all the extracted MeSH terms, 41 high frequency ones were identified and hotspots were clustered into four categories. In the strategic diagram, research on intrauterine treatment of MPR was most well developed. In contrast, statistical data on the sequelae of fetal reduction surgery and applications of MPR in assisted reproductive technologies were relatively immature. Conclusion The analysis of common terms among the high‐frequency network terms in multiparous pregnancy reduction can help researchers and clinicians understand the hotspots, key topics, and issues to be discovered on MPR. Research on intrauterine treatment of MPR was most well developed.
Virtual poster abstracts Methods: Case note review of all cases from May 2014-October 2019. Results: FLA for TTTS was performed in 46 women at 16-26 weeks gestation. The median Quintero stage at FLA was II. 38 women underwent fetal neurological MRI assessment subsequent to their laser therapy and eight women did not undergo fMRI (three patients had an intrauterine loss of both fetuses; four patients delivered prior to planned fMRI and one patient declined fMRI). Of the 38 women undertaking MRI assessments: 25 had two surviving fetuses and 12 had one surviving fetus, with a total of 63 fetuses assessed. The fMRI was performed at a median gestation 26 weeks (range 23-30 weeks) post-FLA. fMRI demonstrated macroscopic brain abnormalities in 6% (4) of imaged fetuses: mild ventriculomegally (1), reparative microgyria (2) and small volume germinal matrix bleed (1). These were likely to be sequelae of TTTS plus or minus its therapy by FLA. Conclusions: 6% of fetuses assessed by interval fetal MRI had evidence of macroscopic neurological findings on fMRI. This data supports the known literature of neurological sequelae of TTTS and antenatal imaging of these babies has allowed for tailored neurodevelopment follow-up. VP43.02 Predictive value of twins' umbilical intercord distance for complications in monochorionic twin pregnancy
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