Struma ovarii is a rare variety of specialized monodermal mature ovarian teratoma, it is composed predominantly of thyroid tissue. Ascites is present in one third of patients. The combination of struma ovarii, marked ascites and elevated CA125 is a rare condition, which may mimic ovarian cancer. We described two cases presenting with pelvic mass, ascites and elevated serum CA125 levels, frozen section and final pathology turned out to be struma ovarii. Ascites disappeared and the level of CA125 returned to normal level after operation. One of the cases was associated with pleural effusion, leading to a condition called pseudo-Meigs’ syndrome. Then we reviewed the related literatures to explore the possible mechanism of ascites and pleural effusion, the reason of CA125 elevation and imaging manifestations of struma ovarii. In conclusion, struma ovarii should be considered in the differential diagnosis preoperatively, when presented with pelvic mass, ascites and an elevated CA125 level.

To compare the clinical outcomes and endocrinological characteristics of progestin-primed ovarian stimulation (PPOS) protocol using medroxyprogesterone acetate (MPA) 8mg versus 4-6mg daily in POSEIDON group 3 and 4. This was a retrospective cohort study. Low-prognosis women from POSEIDON group 3 and 4 using MPA high-dose(8mg/d) or low-dose(4-6mg/d) in PPOS protocol who underwent IVF/ICSI at the Reproductive Medicine Center of the First Affiliated Hospital, Fujian Medical University from February 2019 to February 2022 were recruited. The primary outcome measure was the incidence of premature LH surge. The secondary outcome measures included the embryo results and clinical pregnancy outcomes. Baseline characteristics of patients were similar in the MPA high-dose(8mg/d) group and MPA low-dose(4-6mg/d) group both in POSEIDON group 3 and group 4. In POSEIDON group 3, there was no significant difference in the incidences of LH surge between the high-dose group and the low-dose group (11.1% vs. 6.8%). No significant differences were observed in the number of oocytes retrieved (4(3,6.25) vs. 5(3,7)), viable embryos (2(1,3) vs. 1(1,3)), clinical pregnancy rate (52.3% vs. 52.5%) and live birth rate (43.2% vs 42.5%) per transfer cycle between the groups. In POSEIDON group 4, the incidence of LH surge was similar between the high-dose group and the low-dose group (6.9% vs. 6.3%). No significant differences were found in the number of oocytes retrieved (3(2,5) vs. 3(2,5)), viable embryos (2(1,2) vs. 1(0,2)), clinical pregnancy rate(34.6% vs 31.9%) and live birth rate(17.3% vs 21.3%) per transfer cycle between two groups. MPA started at 4mg daily and then increased to 6mg daily was as effective as MPA 8mg daily in preventing an untimely LH rise in low-prognosis women from POSEIDON group 3 and 4. PPOS using MPA 8mg or 4-6mg daily was comparable in terms of the number of oocytes retrieved and pregnancy outcomes after FET.

This study compared the image quality of single-shot echo-planar imaging (ss-EPI) and readout-segmented echo-planar imaging (rs-EPI) in cervical cancer (CC). ADC values derived from these two sequences were considered as diagnostic capabilities for CC’s lymph-vascular space invasion (LVSI) and lymph node metastasis (LNM). The results showed that rs-EPI images of cervical cancer had higher subjective image quality scores, lower SNR, but no difference in CNR and ADC values. ADC was able to predict the CC’s LNM status，but couldn’t identify the LVSI status. ADC of rs-EPI sequence was superior to diagnose CC’s LNM status.