Liver diseasesLiver diseases and liver damage, which are complications of diseases of the gastrointestinal tract, as well as other organs and systems, which manifest as liver failure, remain a significant problem of modern practical medicine throughout the world.Viral hepatitis is the most common cause of liver failure. According to the WHO, more than 2 billion people are infected with the hepatitis B virus and more than 50million people get infected every year, more than 2million people die. There are 100-200million people with hepatitis C. 1 Infection with hepatotropic viruses B, C, D is the cause of the development of chronic viral hepatitis (CH), which are also among the most common liver diseases. 2,3 Currently, there are more than 180million carriers of chronic hepatitis C and approximately 350million carriers of chronic hepatitis B. 4,5 Despite progress in modern medicine, difficulties remain in diagnosing CH, 6 and adverse clinical manifestations of CH significantly worsen quality of life of patients and reduce its duration. 6 Chronic hepatitis can lead to cirrhosis of the liver, liver failure and the development of hepatocellular liver cancer. 1 -3 Hepatocellular carcinoma is now becoming one him of the most common types of cancer in the world. It ranks sixth in incidence among all malignant neoplasms, making a significant contribution to the third leading cause of cancer mortality in the world. [7][8][9] The liver is the organ that is more often compared to other organs, is exposed to metastatic lesions, especially in cancer of the digestive tract. 10 In pancreatic cancer, liver metastases occur in 50% of cases, gastric cancer metastasizes to the liver in 35% of cases, colorectal cancer from 20 to 50%, breast cancer in 30%, and esophageal cancer in 25%. 10