Contact Urticaria (CU) is a wheal and flare reaction, occurring within few minutes to hours of contact to an external agent over skin or mucosa. Depending on underlying pathophysiology, CU is of two types: immunological CU and non-immunological CU. Use of hand sanitisers has increased multifold in this COVID-19 pandemic, due to increased awareness regarding maintaining a good hygiene to reduce the transmission of infection. This present case is a 24-year-old man, who overzealously added ethanol-based hand sanitiser to his bathing water on the advice of a general physician and after bathing developed redness, swelling and itching on various body parts. A diagnosis of Non-immunological CU (NICU) due to ethanol in sanitiser was made, based on history and clinical examination.

FUE or follicular unit excision is a minimally invasive hair restoration surgery which involves extraction of grafts [Figure 1] from the donor area and implanting them in the recipient area. This technique is currently known to every hair transplant surgeon throughout the world. Even the patients are aware of the procedure and themselves demand it to their treating surgeon, but this was not always the case and FUE has evolved to its current status by many years of trial and meticulous research by the concerned doctors.

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Authors have attempted to provide a short concise and clinically relevant review on premature graying of hairs with the focus of updated pathogenesis, rational investigations, and treatment options. Premature graying of hairs is a fairly common clinical condition faced by dermatologists, however, very scarce therapeutic options are available for successful management of gray hairs. The role of antioxidants is not yet established firmly in the therapeutic armamentarium of premature graying of hairs. Authors have summarized the currently available therapeutic options for the treatment of premature graying of hairs.

Androgenetic alopecia, known alternatively as male pattern baldness when men are affected, and female pattern hair loss, when it affects women, is a form of alopecia characterized by miniaturization – a process wherein thick, long terminal hair are converted to short, thin, miniaturized hair due to the effect of dihydrotestosterone. Various pathogenetic mechanisms exist that support the process. Due to the unusually high disease burden and the psychosocial affliction, a lot of research in underway in the field. Clinically, this subtype of patterned hair loss presents with typical and atypical patterns presenting with thinning of hair and / or balding, or both. It is of paramount importance to recognize and grade the disease early to administer appropriate therapy. Trichoscopy also plays a major role in diagnosing, prognosticating and even monitoring patient response to therapy.