Globally, there is a rising prevalence of infertility, and it has a negative consequence on the quality of life of women. The researchers aimed to understand the knowledge, attitude, and practice of women with infertility toward exercises. A cross-sectional study was conducted on 332 women aged between 18 and 45 years attending an infertility clinic in a tertiary hospital in Southern India. Participants filled a self-developed, content validated, pilot-tested questionnaire. Informants perceived stress and weight gain to be the major causes of infertility. Exercise was believed to improve fertilization by 55.4% of the participants, and walking and yoga were the preferred mode of exercises. BackgroundInfertility is a disease of the reproductive system defined as a failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse (Zegers-Hochschold et al., 2009). Although, there is a decline in fertility from 2.52 births per woman in 2010-15 to 2.47 in 2015-2020 globally, a further decline in the total fertility rate is seen in India from 2.7 births per woman in 2005-06 to 2.2 births in 2015-16 (International Institute of Population Sciences, 2017; United Nations, Department of Economic and Social affairs, Population division, 2017). Polycystic Ovarian Syndrome (PCOS), endometrial tuberculosis, pelvic inflammatory diseases, tubal infertility, late marriages, and sedentary behaviors are identified as the risk factors associated with infertility in India