A safe approach for fabrication silver nanoparticles has established. In this approach a grape fruit peel extract was employed to serve as a capping agent to reduce the aggregation process of Ag nanoparticles. The formation of Ag nanocrystal was confirmed by the color change from yellow to brownish red after 24-hour incubation. The red shift of SPR band position (∼455 nm) compared to the bulk silver (420 nm) indicates the formation of silver nanoparticles. The size and morphology of Ag nanoparticles were characterized by scanning electron microscopy. The SEM images revealed that the prepared Ag nanoparticles have a diameter of 50-70 nm, while the cubic-like shapes are dominated. Fourier Transform Infrared Spectroscopy (FT-IR) was employed to characterize the prepared Ag nanoparticles.