The use of pesticides against the Mediterranean fruit fly, Ceratitis capitata (Wiedemann) (Diptera: Tephritidae) as a tool to control the pest has become an obstacle to the fresh agricultural products export to many countries that restrict pesticides residues. The effectiveness of three local strains of entomopathogenic fungi: Metarhizium anisopliae, Beauveria bassiana, and Paecilomyces lilacinus against the adult and immature stages of C. capitata was evaluated under laboratory conditions. Obtained results showed that M. anisopliae and B. bassiana were superior in its pathogenicity and potential to kill the pest than P. lilacinus. These results may be important to be used for the control of the pest in IPM program.