No abstract

No abstract

Esophageal lesions are rarely seen in patients with intestinal Behçet's disease. Three patients with esophageal lesions (dissection of esophageal mucosa, esophageal ulcer, esophageal varices) were observed among 15 patients with intestinal Behçet's disease or non-specific simple ulcer (1974-1984). Two-thirds of these fifteen patients had fully developed or suspected Behçet's disease, and one-third had no symptoms typical of Behçet's disease. They are classified as non-specific simple ulcer. The average age of the 15 patients was 43 years, all patients but one were male. The recurrence rate after surgical treatment was 70%, that of medical treatment was 90%.

No abstract

Aim: We investigated the developmental factors of fibrous opacification in the atopic cataract lens capsule. Method: We examined the expression of transforming growth factor (TGF)-β signals (phosphorylated Smad2/3 and Smad7) and plasminogen activator inhibitor (PAI)-1 in atopic cataract lenses by immunohistochemistry. The PAI-1 concentration in aqueous humor was also measured. Results: Lens epithelial cells of the atopic cataract lens capsule showed positive immunohistochemical staining for phosphorylated Smad2/3 and Smad7. Lens epithelial cells of the age-related cataract lens capsule were positive for phosphorylated Smad2/3, but negative for Smad7 by immunohistochemistry. All cells were negative for PAI-1. However, high concentrations of PAI-1 were detected in the aqueous humor of atopic cataract patients. Conclusion: We suggest that TGF-β and PAI-1 contribute to fibrous opacification in the atopic cataract lens capsule.