Objectives The aim of this systematic review and meta-analysis was to evaluate fissure sealant retention in clinical studies in which investigators used flowable composites as pit and fissure sealants compared with conventional resin-based pit and fissure sealants.Data sources and data selection The authors conducted a literature search (all articles published until April 13, 2017) to identify studies for inclusion in this systematic review. They assessed the quality of the evidence provided by using the modified Jadad scale and performed meta-analyses by using a random-effects model.Data extraction and data synthesis The authors found 11 studies that met the inclusion criteria for the systematic review and nine studies that could be used for the meta-analysis. Of the 11 studies identified in the systematic review, four scored as having a low risk of bias, and seven scored as having a medium risk of bias. Our meta-analysis showed a significant positive effect of using flowable composites as a fissure sealant material (odds ratio, 2.387 [95% CI, 1.047, 5.444; P = 0.039]).Conclusion It seems that the use of flowable composite as a fissure sealing material can slightly increase the retention rate of sealants compared with conventional resin-based sealants.

This study was conducted to assess the efficacy of ultrasound in the diagnosis of acute appendicitis in clinically suspected cases of acute appendicitis. A total of 110 patients clinically suspected to have acute appendicitis admitted to the surgery departments of Golestan and Imam Khomeini hospitals, from March 2006 to 2007. Abdomino-pelvic ultrasonography with focus on RLQ ultrasonographying the graded compression technique was done. Positive ultrasonography was defined as at least one of the criteria of puylaert. The sonographic data were prospectively correlated with clinical, operative and pathological findings. Graded compression ultrasonography results were analyzed and remarked 92.7% sensitivity, 94.5% specificity, 93% accuracy, 94.4% positive predictive value and 92.5% negative predictive value. Ultrasonography is an accurate, safe and reliable method in the diagnosis of suspected cases of acute appendicitis that can help to minimize negative appendectomies and perforation rates.