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and rate of rise ofmelanoma mortality are known. One group is then subjected to educational material to which the control group is not exposed and changing patterns of presentation and mortality compared in the two groups. Although this is what was originally planned in Scotland, it was quickly apparent that television was by far the most powerful educational medium, and television channels are relatively unrestricted in their distribution. Furthermore, a story regarded as newsworthy in one area is quickly publicised by television, radio, and newspapers in adjacent areas. In addition, organisers of campaigns such as this have no control over the spread of information in the secondary wave of publicity in women's magazines, etc. Thus, although not ideal, it was necessary to accept the compromise of changes in thickness and mortality in the intervention group before and after intervention as a reasonable measure of efficacy. ConclusionIn conclusion, audit of the west of Scotland melanoma education campaign shows encouraging evidence that for women the appropriate population has been targeted and patients are now attending for treatment with thinner primary melanomas. The number of thick melanomas diagnosed in women and the melanoma related mortality in women both showed a downward trend. Alternative approaches seem to be needed to achieve a similar result in men. Abstract Objective-To test whether a fat reduced diet rich in soluble dietary fibre, antioxidant vitamins, and minerals reduces complications and mortality after acute myocardial infarction.

Aneurysmal bone cyst is a rare tumour-like lesion which develops during growth. Our aim was to determine the efficacy of the administration of percutaneous intralesional 3% polidocanol (hydroxypolyaethoxydodecan) as sclerotherapy. Between July 1997 and December 2004 we treated 72 patients (46 males, 26 females) with a histologically-proven diagnosis of aneurysmal bone cyst, at various skeletal sites using this method. The sclerotherapy was performed under fluoroscopic guidance and general anaesthesia or sedation and local anaesthesia. The mean follow-up period was 34 months (26.5 to 80). The patients were evaluated using the Enneking system for functional assessment and all the lesions were radiologically quantified into four grades. The mean age of patients was 15.6 years (3 to 38) and the mean number of injections was three (1 to 5). Ten patients were cured by a single injection. The mean reduction in size of the lesion (radiological healing) was found to be 76.6% (61.9% to 93.2%) with a mean clinical response of 84.5% (73.4% to 100%). Recurrence was seen in two patients (2.8%) within two years of treatment and both were treated successfully by further sclerotherapy. Percutaneous sclerotherapy with polidocanol is a safe alternative to conventional surgery for the treatment of an aneurysmal bone cyst. It can be used at surgically-inaccessible sites and treatment can be performed on an out-patient basis.

Background Minimally invasive approaches such as sclerotherapy have been introduced to treat aneurysmal bone cysts. Sclerotherapy has been associated with reasonable healing rates during the past two decades. However, it is unclear whether sclerotherapy compares with the more traditional extended curettage and bone grafting. Questions/purposes We therefore compared the healing rates and functional scores in patients having percutaneous repetitive sclerotherapy using polidocanol (Group 1) with those with intralesional excision (extended curettage with a high-speed burr) and bone grafting (Group 2) for treatment of aneurysmal bone cyst. Patients and Methods We randomly divided 94 patients into two treatment groups. We assessed healing rates (primary outcome measure), pain relief, time to healing and recurrence, hospital stay, and the Enneking functional score. Forty-five patients from Group 1 and 46 from Group 2 were available for study. The minimum followup was 3.2 years (mean, 4.4 years; range, 3.2-6

Lower consumption of dietary zinc and low serum zinc levels were associated with an increased prevalence of CAD and diabetes and several of their associated risk factors including hypertension, hypertriglyceridemia and other factors suggestive of mild insulin resistance in urban subjects.