Eruptive vellus hair cysts were first described in 1977. They usually appear as yellow to reddish-brown papules on the chest. Usual onset is between ages 17 and 24 years, but they may be congenital. Some believe that they may be inherited as an autosomal dominant disorder. Histologically the cyst has a stratified squamous epithelium and it contains laminated keratin and vellus hairs. They are felt to be caused by an abnormality at the infundibular level of the vellus hair. We present this because of this patient's unusual distribution of eruptive vellus hair cysts.
Amino resins are an important class of resins with diverse applications
in the paints and coatings industry. Butylated urea formaldehyde (BUF)
resins are amino resins whose end use is directly dependent upon the
precise control of its properties. Here, we develop a holistic approach
through which we tune BUF chemistry, pH, and reactor conditions to
predict the evolution of various resin properties like molecular weight,
alkoxy functionalization, degree of butylation, and so forth. Specifically,
we develop a reaction mechanism for the condensation step and rate
kinetics for a semibatch reactor using a generic framework. Furthermore,
we perform end-to-end simulations of BUF synthesis, together with
the kinetics of the addition step, and use experiments to determine
rate constants and model validation. Through our simulations, we demonstrate
the synthesis of BUF with targeted properties like resin with high
alkoxy functionalities. As our approach is derived from fundamental
chemistry, it can significantly contribute toward the “on-demand”
synthesis of resins, designed for a particular application.
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