Dementia includes a wide range of neurodegenerative diseases which leads to various complications of the brain functioning. It is a clinical syndrome wherein gradual decline of mental and cognitive abilities occurs and this in a way renders an individual insufficient to function on his own due to severe memory loss. Various types of dementia are Parkinson's disease with dementia (PDD), Lewy body dementia (LBD), Vascular dementia (VaD), Huntington's Disease with dementia (HD), Frontotemporal dementia (FTD), Creutzfeldt-jakob dementia (CJD) and Alzheimer's disease with dementia (ADD). Medicinal plants used in dementia show varied mechanisms including effects on β-Amyloid plaque formation, Acetylcholinesterase (AChE), ɑ and β-secretase, NMDA receptors, glutathione levels and cerebral blood flow. There have been a lot of medicinal plants used for trials against dementia and most of them have shown to have promising results in-vitro. This review article is about different medicinal plants which can potentially treat dementia.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.