The diagnosis of a non-surgical cause of delayed passage of meconium in a neonate may be challenging to the pediatric surgeon. The usefulness of determining trypsin activity (TA) in stool and duodenal aspirate for the diagnosis of cystic fibrosis (CF) and the existence of an entity called transient deficiency of trypsin (TTD) was assessed in 49 neonates over a 14-month period. TA was determined by a gelatin liquefaction technique. An absence of TA was considered if gelatin liquefaction was seen at a dilution of less than 1:100. Neonates with negative activity in both samples were started on supplementary pancreatic enzymes (pancreatin) for 1 month. TA was retested in the stool after stopping pancreatin for 1 week. Neonates with a return of TA were considered to have TTD; those who showed persistent TA deficiency at re-evaluation were investigated for CF by sweat iontophoresis. Twenty-one neonates had negative TA (in 1 only stool was tested); 13 could be re-evaluated (4 died, 4 were lost to follow-up). Nine were found to have TTD as a stool or duodenal sample showed the presence of TA; 3 of 4 patients with persistent negative TA were confirmed to have CF. One patient with normal sweat chloride is awaiting genetic studies. Determination of TA by gelatin liquefaction is a simple, rapid, inexpensive, and reliable (sensitivity 100%, negative predictive value 100%) means to differentiate non-surgical causes of intestinal obstruction such as neonatal and postoperative TTD and CF.
Beauty is either skin deep i.e. Superficial or the purity of soul itself the later which is implied to Satwa Guna is penultimate and is beyond physical afflictions. Complexion, color etc. attributed to the healthy status of Tawk (skin) and the humors and the former is mean of sensory perception and the Vata Dosha pervades in it. People who live in urban areas and in climates with low humidity seen to be at increased risk for developing atopic dermatitis. W.H.O reveals that more than 75 million people all over the world have this disease.
Kamala is a one among the Rakta Pradoshaja Vikara, where there is aversion towards all desires. Two types of Kamala are mentioned in Ayurvedic classics viz Kostashakhashrita Kamala and Shakhashrita Kamala. Kostashakhashrita Kamala in its definition includes the condition which is mentioned as viral hepatitis in western system of medicine. The treatment modalities described in Ayurveda for Kostashakhashrita Kamala include both Shodhana and Shamana. This study is an attempt to evaluate the efficacy of Nimba, Amrita, Bhumyamalaki, Bhringaraja and Katuki (NABBK) Kashaya and compare its efficacy with that of Nimba, Amrita, Bhumyamalaki, Bhringaraja (NABB) Swarasa with Katuki Churna in Kostashakhashrita Kamala vis-à-vis Viral Hepatitis. Overall difference between two groups showed statistically non-significant result with ‘p’ value 0.953.
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