Vatarakta is one of the main articular diseases, which is characterized by severe pain, tenderness, inflammation and burning sensation in the affected joints. It is a tridoshaja vyadhi, with vata pradhanyata and rakta as main dushya. Sedentary lifestyle is one of the etiological factors of Vatarakta. The etiology and symptomatology of Gout is very much similar to that of Vatarakta. Gout is a pathological reaction of joint or periarticular tissues which results from deposition of monosodium urate monohydrate crystals in joints and tissues. In Ayurvedic classics, although we find plenty of dravyas for joint disorders, the area of joint diseases management still remains to be elusive. Hence the present clinical study aims to evaluate the efficacy of combined effect of 'Guduchi extract and cucumber juice extract' in the management of Vatarakta (Gouty arthritis). In the present study, 20 patients fulfilling the diagnostic criteria of Vatarakta and who met the American College of Rheumatology (ACR) criteria for acute Gouty arthritis were selected. Detailed profile which incorporated relevant data like symptomatology, physical signs and investigation reports were considered for assessment criteria. The ‘Guduchi Yoga’ (Aqueous extract of Guduchi and Trapusha) was administered to patients of either sex in the dosage of 1 g BID with lukewarm water after food for 12 weeks (3 months). After the course of therapy for 12 weeks, symptomatic improvement was observed with statistically significant results (P < 0.001) along with attainment of normal serum uric acid levels followed by feeling of general wellbeing. From the present study it can be concluded that the combined effect of Guduchi and Trapusha extracts showed promising results in the management of vatarakta

Myocardial infarction is one of the highest confronting metabolic syndromes which cause morbidity and mortality across the world. Recently, the renewed interests in medicinal plants have certain preventive action in treatment of cardiovascular disorder.

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Sthoulya (Obesity) is a global problem and it is common among those who consume excessive medokaraahara and vihara. We find no satisfactory remedies for Sthoulya in contemporary medical science. The major health consequences associated with obesity are NIDDM, raised cholesterol, hypertension, coronary heart disease, gall bladder disease, psychological disturbances and certain types of cancer. These diseases are definitely associated with an increased risk of mortality. As it is suitable remedy for Sthoulya mentioned in Charakasamhitha and in all available in Ayurvedic literature. Thus, Bilva-patraswarasa was taken up as remedy for disease Sthoulya in department of Dravyaguna, JSSAMC and H, Mysore, India. The patients were administered Bilvapatraswarasa 30 ml with 12 ml of madhu in early morning on empty stomach daily for 12 weeks for first group. For second group the 500 mg placebo capsule with madhodaka, tid, before food was administered for 12 weeks. Both groups were advised with moderate kilocalorie diet and physical activity intervention (PAI). During the present clinical study was observed that change in weight under the test group patients is significant from 15th day itself. But it is highly significant from 30th day onwards. Even through reduction of weight is observed in control group when compared to test group it was very meager. Bilva-patraswarasa has a significant role to play in the management of Sthoulya. Regain of general improvement of health was significant, no side effects of with drawl effects were observed