Background: CDK10 is involved in cell proliferation; however, the function of CDK10 in cell development remains unclear. Results: The knockdown of cdk10 results in the apoptosis of neural progenitor cells (NPCs) through enhanced raf1a expression. Conclusion: Zebrafish cdk10 exhibits an important function in neurogenesis by the modulation of the raf1a level during development. Significance: These findings emphasize the significance of cdk10 in NPC survival.
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