Disaster is a threat to human life. Many losses are caused by disasters, namely loss of life, injured people, loss of homes, and others. In addition, the frequency and intensity of disasters are also increasing every year. Therefore, research on Disaster Risk Reduction (DRR) is needed both to reduce disaster risk and to manage the disaster. The purpose of this research is to develop an appropriate DRR model in an area to assist decision-making in making policy. This research was compiled based on literature studies from various reputable journals to be used as a reference in the preparation of the right model. Then proceed with the development of a framework to model an efficient and effective DRR. The steps for making a holistic DRR model have been identified and the test design for the model has been determined, namely simulation, validation, and scenario. The recommendation given from this study is the preparation of a DSS (Decision Support System) as a tool for decision-makers to make policies regarding DRR-based regional development. This discussion will be continued in the next research by including case studies in certain urban areas.