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In this paper, we investigate the non-orthogonal multiple access (NOMA) and massive multiple-input multiple-output (M-MIMO) techniques and through simulation, and a comparison is given between the NOMA and orthogonal multiple access techniques. Integrating NOMA with M-MIMO is a very challenging task. In this paper, for a single-cell system, NOMA is integrated with a M-MIMO system for better spectral and energy efficiency. Investigation of the multiple user gain is the focus of this work because the multiple user gain supports simultaneous transmission of multiple users in the case of the M-MIMO system. In this way, the M-MIMO will provide a 100 times channel capacity increase, which results in very high data transmission rate. In the modern communication system, achieving multiple user gain is a very difficult task when channel estimation error is present. The performance of the orthogonal multiple access as well as NOMA system significantly reduced in the presence of channel estimation error. However, most of the current schemes do not work well with imperfect perfect channel state information conditions. Simulation results closely agree with the theoretical outcomes.

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