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Three differently substituted naturally occurring, biologically active carbazole derivatives viz. ekeberginine, murrayaquinone A and glycozoline were synthesized in good yield using short and simple routes. Prenyl group was selectively introduced at C4 position using Stille coupling reaction in the synthesis of ekeberginine. Murrayaquinone A was synthesized using Raney nickel mediated desulfurization of dithiane as a key step.Synthesis of glycozoline was achieved in two steps from 3-methyl carbazole via an intermediate 3-bromo-6-methyl carbazole.

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