Eccrine poroma is a benign adnexal tumour of the uppermost portion of the
intraepidermal eccrine sweat gland duct and acrosyringium. Eccrine porocarcinoma is
the malignant phenotype arising from the intraepidermal portion of the eccrine sweat
gland duct epithelium or from pre-existing eccrine poroma. Both commonly occur in the
palms or sides of the feet; these areas have a high concentration of eccrine sweat
glands. We describe two respective cases of benign and malignant eccrine poroma on
the scrotum, which entailed good excisional results.
Phacomatosis pigmentovascularis is a rare, congenital condition characterized by a
combination of cutaneous melanocytic lesions and vascular malformation. We discuss an
entirely unique case of Phacomatosis pigmentovascularis with nevus of Ota, extensive
Mongolian spot, nevus flammeus, nevus anemicus and cutis marmorata telangiectatica
congenita, which may represent a heretofore undescribed variant of phacomatosis
pigmentovascularis.
Immunoglobulin light chain amyloidosis is the most common acquired systemic
amyloidosis. Its presentation is often insidious and progressive, which may delay
diagnosis. The authors describe a rare case of immunoglobulin light chain amyloidosis
in a 34-year-old man with scleroderma-like manifestation substantiated by
multifarious laboratory investigations and the histopathologic feature of involved
skin lesions stained with Congo red and crystal violet. This helps to maintain a high
clinical suspicion of the disease when confronting similar skin presentation.
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