Quantum key distribution (QKD) networks hold promise for sharing secure randomness over multi-partities. Most existing QKD network schemes and demonstrations are based on trusted relays or limited to point-to-point scenario. Here, we propose a flexible and extensible scheme named as open-destination measurement-device-independent QKD network. The scheme enjoys security against untrusted relays and all detector side-channel attacks. Particularly, any users can accomplish key distribution under assistance of others in the network. As an illustration, we show in detail a four-user network where two users establish secure communication and present realistic simulations by taking into account imperfections of both sources and detectors.
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