In the current social context, information technology, network technology, and cloud computing have been widely used in all walks of life. The analysis of the specific application results of progressive technology shows that the use of technology has changed the working state of various industries and improved the work efficiency and quality of the industry. It should be noted that although the application of some technologies will bring many positive belongings, the potential risks brought by them cannot be ignored. As far as the hospital is concerned, the information system using cloud computing technology can make better use of the hospital’s information data, but after the information system is on the cloud, new problems will appear in network security, resulting in the leakage of hospital patient information or research information. Based on this, in practice, it is necessary to analyze the network security problems after the hospital information system goes to the cloud and build and implement the corresponding strategies. The author analyzes and discusses the corresponding contents through work practice and combined with previous articles, in order to provide guidance and help for peers.