PURPOSE: To compare the visual and refractive outcomes in myopic LASIK between wavefront-guided and traditional treatment. METHODS: The study included 162 eyes of 81 myopic patients undergoing LASIK by one surgeon. The right eye of each patient underwent customized LASIK with the NIDEK NAVEX laser system (NIDEK, Gamagori, Japan) (study group); the left eye of each patient underwent traditional LASIK with the NIDEK CXII excimer laser system (control group). RESULTS: No significant differences were noted in refractive error, uncorrected visual acuity, and best spectacle-corrected visual acuity after surgery between the two groups (t test, P > .05). Postoperatively, 3.7% of patients in the study group reported glare, which was significantly lower than 12.4% in the control group (chi-square test, .01 < P < .05). Higher order aberrations increased after surgery in both groups, but less increase was noted in patients in the study group. A statistically significant reduction was noted in the postoperative increase of Zernike coefficients C7, C8, and C12 in the study group compared to the control group (t test, P < .05). CONCLUSIONS: Customized LASIK significantly reduces the rate of postoperative glare and induction of higher order aberrations compared to traditional LASIK. [J Refract Surg. 2005;21(Suppl):S646-S649.]

PURPOSE: To evaluate the visual acuity after LASIK in patients with high myopia and in patients with preoperative best spectacle-corrected visual acuity (BSCVA) <0.6. METHODS: This retrospective study comprised 97 consecutive eyes in 57 patients who underwent LASIK. Preoperative spherical refractive error ranged from -1.75 to -22.00 diopters (D) (mean: -11.77±3.61 D) with mean astigmatism of -1.54 ±10.6 (range: 0 to -4.00 D). Pre- and postoperative BSCVA and uncorrected visual acuity (UCVA) were measured and analyzed. RESULTS: The mean preoperative BSCVA was 0.54±0.07 (range: 0.3 to 0.6). The mean postoperative BSCVA was 0.75±0.16 (range: 0.5 to 1.2). The mean postoperative UCVA was 0.60±0.25 (range: 0.5 to 1.2). A statistically significant improvement was noted in the mean postoperative BSCVA compared with the mean preoperative BSCVA (t= 12.78; P<.001) and mean postoperative UCVA compared with preoperative mean BSCVA (t=2.866; P<.01). The safety index was 1.38, which was statistically significant (P<.001). The efficacy index was 1.11, which was statistically significant (P<.01). CONCLUSIONS: LASIK improved the mean postoperative BSCVA and UCVA compared with preoperative BSCVA in highly myopic eyes with reduced BSCVA. [J Refract Surg. 2006;22:S1053-S1055.]

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