Infants born with potentially life-threatening conditions of omphalocele and gastroschisis may require long-term hospitalization. We aimed to compare the outcomes of these two conditions occurring over a 16-year period (2001-16). It is a retrospective study of 19 newborns undergoing surgery for these two abdominal wall defects (8 patients with omphalocele and 11 cases of gastroschisis). The average birth weights for the newborns with omphaloceles and gastroschisis were 2554.5 g and 2248.6 g respectively. Associated anomalies included trisomy 18, Beckwith-Wiedemann syndrome, congenital heart disease, Meckel’s diverticulum, inguinal hernias, renal deformities, limb deformities, cryptorchidism, body stalk anomalies, and closed gastroschisis. The average hospital stay for the newborns with omphaloceles and gastroschisis were 42.6 days 50.2 days respectively. The time to the start of postoperative nutritional supplementation for the newborns with omphaloceles and gastroschisis were 4.3 days for the infants with omphaloceles and 7.3 days for respectively. The survival rates for the newborns with omphaloceles and gastroschisis were similar, 87.5% and 81.8% respectively. Survival rates in omphalocele correlated negatively with associated anomalies. In gastroschisis cases, strict care is necessary when intestinal dilation is observed via fetal sonography.

Objective: Focal intestinal perforation (FIP), which is characterized by the lack of inflammatory infiltration peripheral to the perforation, develops with few premonitory symptoms. The treatment typically involves laparotomy for drainage or percutaneous drain insertion. We retrospectively investigated the efficacy and risks associated with laparotomy-assisted drainage and peritoneal drainage (PD) for FIP. StudyDesign: This was a retrospective, comparative study.Results: We retrospectively evaluated seven infants with FIP who were admitted to the neonatal intensive care unit between April 2007 and March 2017. Five infants were administered indomethacin and six were administered steroids. The PD group had significantly higher birth weight, higher C-reactive protein (CRP) levels, and shorter operating times. In addition, they gained weight postoperatively but often required adjuvant therapy for bowel function. There was no significant difference between the groups regarding the time to post-operative full feeding, and all infants showed improved physical appearance.Conclusions: PD under local anesthesia can be considered for treating infants with FIP who have elevated CRP levels and poor general condition. We think management of this condition is still challenging in our experience, and it is necessary to continue in the future.