An asymmetric α-C–H alkenylation of aryl alkenes has been disclosed to provide axially chiral aryl 1,3-dienes, proceeding through six-membered exo-cyclopalladation, assisted by an aldehyde/l-t-leucine derived transient chiral auxiliary.

We present a Pd-catalyzed atroposelective preparation of aryl 1,3-dienes from readily available styrenes and olefins through aldehyde derived transient chiral auxiliary, proceeding by enantioselective olefinic C-H alkenylation of styrenes via...

We report on N,N-bidentate-chelation-assisted α- and β-olefinic C-H alkenylation of aryl alkenes in ethanol to afford aryl dienes/trienes with excellent regio- and stereo-selectivities. The reaction of 2-alkenyl benzylamine and benzoic...

Building long-lasting antimicrobial and clean surfaces is one of the most effective strategies to inhibit bacterial infection, but obtaining an ideal smart surface with highly efficient, controllable, and regenerative properties still encounters many challenges. Herein, we fabricate an ultrathin brush–hydrogel hybrid coating (PSBMA-P(HEAA-co-METAC)) by integrating antifouling polyzwitterionic (PSBMA) brushes and antimicrobial polycationic (P(HEAA-co-METAC)) hydrogels. The smart bacterial killing–releasing properties can be achieved independently by the opposite volume and conformation changes between the swelling (shrinking) of P(HEAA-co-METAC) hydrogel layer and the shrinking (swelling) of PSBMA brushes. The friction test reveals that both METAC and SBMA components support great lubrication. By tuning the initial organosilane (BrTMOS:KH570) ratios, the prepared PSBMA-P(HEAA-co-METAC) coating exhibits different antibacterial abilities from single “capturing–killing” to versatile “capturing–killing–releasing.” Most importantly, 99% of the bacterial-releasing rate can be easily achieved via 0.5 M NaCl treatment. This smart surface not only possesses long-lasting antibacterial performance, only ∼1.09 × 105 cell·cm−2 bacterial residue even after 72 h exposure to bacteria solutions, but also can be regenerated and triggered between water and salt solution multiple times. This work provides a new way to fabricate antibacterial smart hydrogel coatings with bacterial “killing–releasing” functions and shows great potential for biomedical applications.

Acylsilane represents one valuable synthon in synthetic chemistry. We report on ruthenium(II)-catalyzed ortho-C−H amination of aroylsilanes to provide facile access toward synthetically useful imidobenzoylsilanes and tosyl-amidobenzoylsilanes. The protocols, occurred with...