ABSTRACT:The lungs are involved in various kinds of inflammatory, neoplastic and other lesions, but they are secondarily involved in almost all form of terminal diseases. Autopsy has a role in the development of new understanding of old diseases and provision of opportunity to discover new diseases. AIM: To present the pulmonary histopathological pattern identified in autopsy. METHODOLOGY: This is a prospective study done in the Department of Pathology, GMC Jammu over a period of 1 years from 2013 to 2014. Materials for study consisted of lungs from 150 cases from medico-legal autopsies received during this period. Gross features were recorded and microscopic diagnosis were made. Results: Among the 150 lung specimens from medicolegal autopsies, 132 were males and 18 were females Findings of lung disease were seen in 138 cases, of which pulmonary edema in 39 cases, DAD in 32 cases Acute Pulmonary congestion in 26 cases, chronic ILD in 12 cases, acute pneumonia in 8 cases, Tuberculosis in 5 cases. CONCLUSION: Histomorphological study of lung in medicolegal autopsies may quite often reveal some natural disease and its relative contribution towards death.
Background: Intestinal atresia forms one of a common cause for intestinal obstruction in neonates. There is a debate about its pathogenesis and many theories have been suggested. Studies regarding its clinical and histomorphological features are less in Indian literature. The present study aimed to determine the clinical and histomorphological features of cases of intestinal atresia.Methods: Thirty-nine cases of intestinal atresia were studied both retrospectively (twenty-six) and prospectively (thirteen) over a period of two years. Their clinical and histomorphological features were studied.Results: Intestinal obstruction was most common clinical diagnosis. Type II atresia was most common. Ileal atresia was highest in number. Associated congenital anomalies noted were situs inversus with splenunculi, patent vitelo-intestinal duct, duplication cyst, Meckel’s diverticulum, ileocecal web, duodenal web and omphalocele. Histological features such as inspissated meconium, calcification, ulceration, fibrosis, thick-walled vessels, edema were noted.Conclusions: Findings such as mucosal edema, congestion, ulceration, submucosal edema, thick-walled blood vessels, fibrosis, hemorrhage, transmural ischemia, calcification, suggest that an intra vascular accident may be responsible for origin of the atresia.
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