Objectives To appraise the effectiveness of platelet-rich fibrin (PRF) in the management of established dry socket in terms of pain, inflammation, and wound healing. Materials and Methods Two hundred patients with established alveolar osteitis were studied to determine the efficacy of PRF and zinc oxide eugenol (ZOE) for pain control, inflammation reduction, and wound healing. Patients were randomly allocated to Group A (PRF) or Group B (ZOE). Patients were examined on the 1st, 3rd, 7th, and 14th postoperative day and evaluated for pain using visual analogue scale scores, inflammation with a gingival index score, and wound healing through a determination of the number of bony walls exposed. Results Group A showed better results in terms of pain remission, control of inflammation, and wound healing compared to Group B. Results between groups were statistically significant ( P <0.05). Conclusion PRF is a better alternative than ZOE for the effective management of alveolar osteitis.

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Objective: Local anesthetics are the most effective drugs available for the management of pain while performing operative procedures. This study was performed to compare the clinical efficacy of treatment with local anesthetic articaine (4%) with ketamine and local anesthetic articaine alone (4%) for the relief or prevention of postoperative pain, swelling, and trismus after the surgical extraction of impacted mesioangular third molars. Materials and Methods: Sixty patients undergoing the extraction of impacted mesioangular mandibular third molars were included in the study. The patients were randomly divided into two groups: local anesthetic alone (LAA) and local anesthetic plus ketamine (LAK). Results: Facial swelling following surgery on postoperative days was significantly lower in the LAK group than in the LAA group on 3 rd and 7 th postoperative days ( P < 0.05). Mouth opening on the postoperative days was significantly greater in the LAK group than in the LAA group on 3 rd and 7 th postoperative days ( P < 0.05). The pain scores on the visual analog scale at 30 min and 1 h, 4 h, 12 h, and 24 h after the surgery were significantly higher in the LAA group than in the LAK group and there was no significant difference in heart rate, oxygen saturation, and blood pressure in both the groups. Conclusion: In this present study, the effect of articaine with ketamine in comparison with articaine alone intraoperatively and postoperatively was observed, and it revealed that the combination of articaine with ketamine produced good local anesthesia and provide good postoperative analgesia with less swelling and significantly less trismus.

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There was an outbreak of a new Coronavirus infection in Wuhan, Hubei Province, China in late December 2019, which caused acute respiratory syndrome of unknown etiology. The World Health Organization (WHO) named the viral causal agent as Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV2) or COVID-19, and declared this infection as a pandemic on the 11 th of March, 2020. The first case of COVID-19 infection in India was reported on late January, 2020, and since then the numbers of confirmed cases have been increasing; thus the government had announced total lockdown of all activities. Most people infected with the COVID-19 virus experience mild to moderate respiratory illness, and recover without the need for special treatments. The elderly people and those with medical problems such as; cardiovascular disease, diabetes, chronic respiratory disease and cancer; are more likely to develop severe illness. Globally, corona virus cases rose to more than 500,000 for the first time on the 27 th of October, 2020. Within two weeks and since 30 th of October, 2020, COVID-19 cases had risen by almost 25 %, and about 400,000 daily cases were reported worldwide. The United States (US) was leading the global corona virus crisis with 8.9 million recorded infections and nearly 228,000 deaths worldwide. Asia had surpassed 10 million infections of the new corona virus on the 31 of October, 2020, and India reported an average of 48,000 cases daily with a total of 8 million cases. The aim of this review was to explore the epidemiological prevalence of COVID-19 in India along with age and gender stratified prevalence of this viral infection.