Transcatheter aortic valve implantation is considered a standard treatment for many symptomatic patients with severe aortic stenosis. Coronary artery occlusion after transcatheter aortic valve implantation is associated with a mortality rate of up to 50%. In this case report we described a patient with severe aortic bioprosthesis dysfunction, at high risk of coronary obstruction after transcatheter aortic valve implantation. This patient underwent Basilica procedure followed by valve-in-valve transcatheter aortic valve implantation. The patient demonstrated good improvement and was discharged from hospital after 2 days, without any symptoms. The patient remained asymptomatic at 6 months of follow-up.

We present the first case in Latin America of transcatheter edge-to-edge mitral and tricuspid valve repair in a single procedure, in a patient at high risk for surgery. The patient progressed to heart failure and limitation in her daily living activities when she was submitted to transcatheter mitral and tricuspid valve repair. Six months later, she was asymptomatic and performing her daily living activities. We discuss the most updated recommendations for transcatheter repair when both valvar conditions coexist, and show the knowledge gaps.