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Purpose: This study aimed to examine the relationships between Sense of Coherence (SoC), Coping Strategies and Quality of Life (QoL) of parents of children with autism in Malaysia.Method: Purposive sampling was used to recruit parents of children with autism from 3 Autism Centres run by NGOs. The parents were asked to complete a questionnaire.Results: The results of the study show that SoC and cognitive reframing are important factors that are associated with QoL.Conclusions: It is recommended that policy-makers and programmers at the Autism Centres conduct more training workshops for parents of children with Autism Spectrum Disorder (ASD), so that their overall QoL can be improved.Limitations: Future studies could recruit more participants, especially parents at government centr

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