The main finding of the present study was the improved endurance gain in BALB / C mice, following the application of a patch (T-NES®-HIT Tech.), enriched with an active central pad, based on micronized silver. In order to transfer very thin Extremely Low Frequency (ELF) magnetoelectric signals, the pad contains a nanotechnological material (silver micronized by plasma vaporization) that is appropriately activated with optical, magnetic, electrical, and acoustic signals. It has been reported previously that the ELF magnetic field, induces an action on cellular glycocalics, fundamental for cellular communication and recognition, and a direct activation of protons and ionic fluxes. The treated animals underwent exercises with Rotarod and several parameters were evaluated and compared with untreated control mice. The following parameters were measured: steady state generic training, long slow distance, high intensity "endurance" and steady state split session training. The ELF magnetic field of T-NES®-HIT Tech. micronized silver patch device, applied to BALB / C mice, markedly improved their endurance gain performance as evidenced by the increase of their aerobic capacity, maximum heart rate and maximum aerobic speed.