Carrot (Daucus carota L.) is a vegetable plant that has many uses for public health services in the world. Fresh carrots contain water, protein, carbohydrates, fat, fiber, ash, anti-cancer nutrients, natural sugars (fructose, sucrose, dextrose, lactose, and maltose), pectin, glutathione, minerals (calcium, phosphorus, iron, potassium, sodium, magnesium, chromium), vitamins (beta carotene, B1, and C) and asparagine. The purpose of this study was to characterize simplicia and carrot seed oil extract, and to determine the antioxidant activity of carrot seed oil extract with formulations of concentrations of 3%, 6% and 9% seeds on the effectiveness of anti-aging Moisture, Evenness, Pore, Spot and Wrinkle. Carrot seed oil can be formulated in a homogeneous cream dosage form with an oil-in-water emulsion type, pH 6.7-7.7; does not cause skin irritation and is stable on storage for 90 days at room temperature. Carrot seed oil cream with a concentration of 9% showed the best anti-aging effectiveness by increasing water content, reducing skin hardness, shrinking pores, reducing blemishes and reducing wrinkles compared to other cream formulas.

Blood transfusion currently plays an important medical role in methods of reducing the number of leukocytes in component products, including reducing the number of leukocytes before storage (pre-storage leucodepletion) and reducing the number of leukocytes after storage (post storage leucodepletion). The purpose of this study was to determine whether there was a comparison of hemolysis events and hematocrit quality in leucodepleted (In Line) and leucodepleted (Bedsite) clinical transfusions at the Blood Transfusion Unit at the Indonesian Red Cross in Medan City. This study was an analytic study with a cross-sectional design of 58 people who were divided into two groups, namely the group with leucodepleted in line and the group with leucodepleted bedsite, inclusion and exclusion criteria. The results showed that the incidence of hemolysis after leucodepleted (in line) was 0% and leucodepleted (bedsite) was 0.02%, where the standard percentage of blood hemolysis was <0.8%, the occurrence of hemolysis after the production process of the two products was very small. While the hematocrit before and after leucodepleted decreased by 35.91% in leucodepleted (in line) and 33.33% in leucodepleted (bedsite). Comparison of leucodepleted (In Line) and leucodepleted (Bedsite) hemolysis events was also found. Where the incidence of leucodepleted (in line) hemolysis is not found, so the leucodepleted (in line) blood component has good quality.