Antibiotics for suspected acute appendicitis are safe and effective and may avoid unnecessary appendectomy, reducing operation rate, surgical risks, and overall costs. After 2 years of follow-up, recurrences of nonoperatively treated right lower quadrant abdominal pain are less than 14% and may be safely and effectively treated with further antibiotics.

Mortality of severe trauma decreased significantly during the last 15 years as well as mean GCS improved whereas mean ISS remained stable. The new safety regulations positively influenced incidence and severity of TBI and seemed to improve the outcomes. ISS seems to be a better predictor of outcome than RTS.

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Herein we describe a rare case of an "orphan" neoplasm arising on an unusual site.During the clinical examination, a mass of 3 cm was found on the left areola of a male patient. It was a solid, sliding on the deep layer, with a bluish color mass; therefore an excisional biopsy was performed. The histopathological diagnosis was nodular malignant hidradenoma. An oncological consulting recommended a surgical radicalization through a radical mastectomy. No adjuvant therapy has been given. The patient is alive with no evidence of disease after one-year follow up.