European Calligraphy has a millennial history that has been marked by various stages and vicissitudes that influence modern aesthetic tendencies in calligraphy and typography. In the forthcoming conference will be presented some interesting examples of fundamental calligraphy scripts and their interpretations, as well as the preparation and realization of illustrations in graphic prints (lithography). The final result are artistic books inspired by Dante Alighieri's Divine Comedy poem, and in particular the Hell part, as well as Gustav Dore's graphics. The books are enriched with specially made cases, that further fortify the creative pursuits of the authors and to arouse interest in the viewer. The interdisciplinary approach and complex tasks, including 3D graphics and virtual reality, present a new read on book, illustration and calligraphy. Keywords: Calligraphy, Interdisciplinary, Virtual Reality, 3D Graphics, Artistic Book, Lithography