Extreme weather damages and disrupts transport infrastructure in a multitude of ways. Heavy rainfall and ensuing landslides or flooding may lead to road or rail closures; extreme heat can damage road surfaces, or cause tracks, signalling or electronic equipment to overheat, or thermal discomfort for passengers. As extreme weather is expected to occur more frequently in the future, transport infrastructure owners and operators must increase their preparedness in order to reduce weather-related service disruption and the associated financial costs. This article presents a two-sided framework for use by any organisation to develop climate-change-ready transport infrastructure, regardless of their current level of knowledge or preparedness for climate change. The framework is composed of an adaptation strategy and an implementation plan, and has the overarching ambition to embed climate change adaptation within organisational procedures so it becomes a normal function of business. It advocates adaptation pathways, i.e., sequential adaptive actions that do not compromise future actions. The circular, iterative structure ensures new knowledge, or socioeconomic changes may be incorporated, and that previous adaptations are evaluated. Moreover, the framework aligns with existing asset management procedures (e.g., ISO standards) or governmental or organisational approaches to climate change adaptation. By adopting this framework, organisations can self-identify their own level of adaptation readiness and seek to enhance it.