The first kidney transplantation was performed in 1951 and ever since then living donor transplantation became a more and more important solution for patients with end-stage renal disease (ESRD).Renal transplantation is a life-saving procedure. Morbidity and mortality on waiting-lists are strongly correlated with the time of dialysis and end-stage renal disease is one of the most important causes of death; this is the reason why transplantation has to be performed as soon as possible in order to reduce the time of dialysis.Once the transplantation is performed, a number of complications may occur in post-transplant evolution, the most important of which is rejection.The rejection may appear through several mechanisms, but one of the most frequent causes of rejection is cytomegalovirus (CMV) infection. It is very important to have a precocious and fast diagnosis of CMV infection in order to maintain the functionality and survival of the graft. PP65 CMV antigenemia has proven its effectiveness in detecting and monitoring the CMV infection in transplanted patients.In the laboratory of the Clinical Institute of Urology and Renal Transplantation (ICUTR) of Cluj Napoca the CMV infection is evidenced by two methods: PP65antigenemia and IgM antibody identification by chemiluminiscence.
Purpose: Trichinellosis, also called trichinosis, is a zoonosis caused by Trichinella spp, a helminth that infects a very broad range of animals. Humans can get the infection by eating raw or undercooked meat with Trichinella larvae encysted in muscle tissues of domestic or wild animals. Symptoms may range from very mild to severe and are related to the number of larvae consumed in the meat. The aim of the present study was to evaluate the prevalence, symptoms and risk factors of human trichinellosis in Western Romania over a period of 4 years (2012)(2013)(2014)(2015)(2016).Methods & Materials: This retrospective study included 23 consecutive patients diagnosed with trichinellosis and hospitalized at "Victor Babeş " Infectious Diseases Hospital in Timiş oara,Romania, between 01.01.2012 -30.06.2016. Medical records of these patients were investigated to collect clinical, laboratory, epidemiological, and therapeutic data.Results: The 23 patients ranged in age from 2 to 61 years (mean = 31.9 years), 12 (52.2%) were males. Fever (69.5%), myalgia (65.2%), weakness (43.4%) and eyelid edema (34.8%) were the most frecquent symptoms. High levels of white blood cells were reported in 10 (43.5%) patients and eosinophil counts ≥ 4% were reported in 21 (91.3%). Wild boar meat was the source of infection in 4 (17.4%) patients and pork meat was the source of infection in 19 (82.6%). In 43.5% of the patients, the hospitalization period ranged between 10 and 17 days and required significant health care resources. Albendazole was the antiparasitic drug administered in 56.5% of the patients.
Conclusion:Trichinellosis still remains an important public health problem in Western Romania. Sanitary education programmes for both swine breeders and consumers and implementation of strict hygienic measures are strongly recommended.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.