Five samples of buriti oil from industrial and artisanal suppliers were characterized in terms of nutritional quality parameters (nutraceutical levels) and acidity. As a first screening, each sample was analyzed by titration, spectrophotometry and an HPLC method, and the results were compared. As expected, artisanal samples showed lower acidity and higher levels of carotenes and tocols (tocopherols and tocotrienols). A blend of industrial and artisanal samples in suitable proportions was completely characterized in terms of analytical and physico-chemical properties, i.e., fatty acid composition, iodine value, partial and total acylglycerol contents, refractive index (40°C), saponification value, unsaponifiable matter, acidity (expressed as % of oleic acid), peroxide value, phosphorus content, oil stability index, tocol and carotene concentrations. The results of the present study showed that buriti oil is a valuable source of monounsaturated fatty acids, and vitamins A and E. No previous work in the literature has analyzed buriti oil to this extent. The chromatographic method using HPLC was effective in qualifying and quantifying tocopherols, tocotrienols and carotenes.
O sistema imunológico humano possui um significado comum de proteção contra antígenos estranhos com potencialidade patogênica ou não, ativando uma ação coletiva e coordenada entre células e moléculas. Embora sendo um sistema benéfico, deve ser controlado para evitar que auto-antígenos sejam alvejados. Recentemente, por meio de novas técnicas, tem-se observado uma corrente de estudo para as células T CD4 + CD25 + Foxp3 como células reguladoras que controlam ativamente a função de outras células imunes impedindo sua atividade e, conseqüentemente, o desenvolvimento de doenças auto-imunes, rejeição de enxerto e combate a células tumorais. Em pacientes submetidos ao transplante alogênico, os mecanismos que levam a hiporresponsividade, assim como os mecanismos que permitem uma maior sobrevida do enxerto ainda são pouco conhecidos. Este artigo aborda uma revisão da literatura sobre as células T regulatórias, vislumbrando uma nova possibilidade de terapia imunomoduladora para pacientes transplantados.
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