The field of nanotechnology is the most renowned area of research in modern day science. One of the most convenient and comprehensive technique related to the synthesis of nanoparticles using plant extracts and their subsequent action. On the other hand, herbal medicines become an integral part of modern-day treatment strategy around the globe; combination of these two ways are widely accepted and beneficial due to its low cost, better societal recognition and less side effects. Phytochemical analysis revealed that leaf aqueous extract of two medicinal plants Oldenlandia corymbosa and Ocimum sanctum, harbours high concentration of antioxidants and bioactive molecules. Hence our present course of study aims at the green synthesis of silver nano-conjugates using Oldenlandia corymbosa and Ocimum sanctum leaf aqueous extracts. The synthesized nano-conjugates have undergone advanced chara-cterization techniques including UV-Vis Spectro-photometry, DLS, and FT-IR. The UV-Vis spectroscopy results showed single peak at 420 nm and 430 nm for Oldenlandia corymbosa and Ocimum sanctum nano-conjugates, respectively. The particle size for Oldenlandia corymbosa and Ocimum sanctum nano-particles are 21.04 nm and 24.36 nm, respectively as observed from the DLS data, and finally, the FT-IR data confirms the conjugation of bioactive molecules of the medicinal plants indicating that primary amines, secondary amines, alcohols, phenols, aldehydes, aliphatic amines, alkenes, functional groups of the bioactive molecules are responsible for the stability of prepared silver nano-conjugates