School as center of adolescent social life has an important role to help students to achieve well-being. But in fact, adolescence is often vulnerable to individual problems such as stress, anxiety, and self-destructive behavior. The current study examined the mediation effect of state and trait anxiety in the association between school burnout and well-being. State-Trait Anxiety Inventory (STAI), School Burnout Inventory (SBI), and Satisfaction with Life Scale (SWLS) was administered to 192 vocational high school students. Mediator analysis using bias corrected bootstrap method N = 5000 and 95% confidential interval on PROCESS software. The results show that school burnout as predictors on well-being students only indirectly via state and trait anxiety. These findings can be beneficial to our understanding of how and when state and trait anxiety impacts student"s well-being, and have implication for development guidance and counseling programs to improve student"s well-being.