Background : Mosquito population is a well-known vector in transmitting many types of diseases causing serious public health problems (Gubler 1995; Lam, 1993; Nazri et al. 2013). Dengue Hemorrhagic Fever (DHF) is a disease caused by Dengue Virus that transmitted y mosquito bites of Aedes aegypti. Prevention of Dengue Hemorrhagic Fever can be done by controlling biological and chemical the vector of larvae stage. The vector has been resistance of chemical insecticides. The most accurate way to control propagation is by using the natural substance, for instance is the Kenikir leaves (Cosmos caudatus Kunth.). The Extract of Kenikir leaves contains of active substance Alkaloid, Saponin, Flavonoid and Tannin which are poisoning to Aedes aegypti L. larvae Objective : The purpose this research to determine the larvacide effect of the Extract Kenikir's leaves (Cosmos caudatus Kunth) against the Aedes aegypti L. as a Dengue Hemorrhagic Fever's vector. Methods : This research used a Completely Randomized Design (CRD) design using 900 larvaes of Aedes aegypti L. instar III and divided into 6 treatments extract group (negative control ; 0,05%, 0,10% ; 0,15% ; 0,20%, positive control) which is in each treatment extracted with 4 replications. Results : The Result of larvicide effect was analyzed by using Analysis of Variance (ANOVA) and Probit Analysis. Result the research showed that Cosmos caudatus Kunth's leaves extract affected the death of the third instar Aedes aegypti larvae with significant value (P <0,05). The Result of probit analysis showed that LC50 value of Cosmos caudatus Kunth's leaves extract was 0,19 %. Conclusion : Larvicide effect of Cosmos caudatus Kunth's leaves extract cause from secondary metabolits such as alkaloid, flavonoid, saponin, dan tannin. The conclusion of this research is Cosmos caudatus Kunth's leaves extract have effectiveness as a larvicide the third instar of Aedes aegypti.

Hypertension in pregnancy is one of the most common causes of maternal death in Indonesia as well as in other developed countries such as the United States. The cause of preeclampsia is currently uncertain, but there are several risk factors that can increase the occurrence of preeclampsia. Coronavirus disease 19 (COVID-19) is caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2). Pregnant women and hypertension are factors that can increase the risk of COVID-19. If not treated properly, hypertension in pregnancy can cause maternal and fetal morbidity and mortality. The purpose of this study was to describe the incidence of maternal hypertension in pregnancy with COVID-19 based on age, parity, gravida, history of preeclampsia, and education at Ulin Hospital Banjarmasin for the period May 2020-June 2021. This research method was descriptive with data collection through medical records. patient. The sampling technique used is total sampling. The subjects of this study amounted to 88 patients. This study shows preeclampsia is the type of hypertension in pregnancy with COVID-19 being the most common, which was 57 patients (64.7%). Most of the patients were in the age range of 20-35 years, as many as 52 patients (59.3%). Based on parity, most of the cases occurred in mothers with multilipara as many as 39 patients (44.3 %). Gravida was found mostly in mothers with multigravida as many as 63 patients (71.6%). Based on a history of preeclampsia, patients who did not have a history of preeclampsia were found to be more than patients who had a history of preeclampsia, namely as many as 52 patients (59.1%) and the majority of patients' education at the high school level, which was 29 patients (32.9%).

Preeclampsia is hypertension in pregnancy which is characterized with blood pressure of 140/90 mmHg after 20 weeks of gestation, accompanied by proteinuria.3. There are three types of drugs that are often used in preeclampsia treatment, they are nifedipine, methyldopa, and MgSO4. This study was aimed to find out the description of confirmed covid-19 and non covid-19 preeclampsia patients treatment at Ulin Hospital, Banjarmasin in the COVID-19 period seen from administration of MgSO4, antihypertensive, method and time of termination. This study applied descriptive method with data collection through medical records. The sampling technique used purposive sampling which was selected based on the criteria. In this study, a sample of 176 preeclampsia patients with confirmed COVID-19 and non-COVID-19 were  obtained. However, from the 176 samples, which met the criteria, only 55 preeclampsia patients had confirmed COVID-19 and 80 non-COVID-19 preeclampsia patients. The results showed that all severe preeclampsia patients with confirmed COVID-19 were given MgSO4 with a percentage of 100%.. Antihypertensives were often given was a combination of methyldopa + nifedipine. The most common method of delivery was by cesarean section.

: In addition to major illnesses, there are cases when a person suffers from other illnesses. This is called comorbid or comorbidity. There are many risk factors for COVID-19, one of which is comorbidities. These comorbidities affect the prognosis for possible COVID-19 infection and disease severity. This study attempts to elucidate the relationship between comorbidities and the incidence of COVID-19 at Pemurus Dalam Urban Health Center in Banjarmasin. This study was designed as an analytical observation and used as a case control approach. A total of 30 subjects were found to meet the inclusion and exclusion criteria in each case and the control group as well as samples were taken using a simple random sampling technique. As a result of the univariate analysis, most of the case group (70%) had normal morbidity compared to the control group, and only a small number (23,33%) showed normal morbidity. Bivariate analysis showed that an OR value of 7,667 with a p value of 0,000 or <0,05 was associated with the incidence of COVID-19 and comorbidities. 7,667 OR value indicate that comorbidities is closely related to the incidence of COVID-19 in Banjarmasin. Keywords: comorbid, the incidence, COVID-19 Abstrak: Selain penyakit utama, terdapat kondisi dimana seseorang memiliki penyakit yang lain, hal ini disebut sebagai komorbid atau komorbiditas. COVID-19 memiliki berbagai faktor risiko, salah satunya adalah komorbid. Komorbid ini memengaruhi mudahnya terjadi infeksi COVID-19 serta prognosis dari beratnya derajat penyakit. Hubungan antara komorbid dengan kejadian COVID-19 di Puskesmas Pemurus Dalam Kota Banjarmasin berusaha dijelaskan pada penelitian ini. Penelitian didesain dengan observasional analitik, serta menggunakan case control sebagai teknik pendekatannya. Sebanyak 30 orang yang sesuai dengan kriteria inklusi maupun eksklusi didapatkan pada tiap kelompok kasus maupun kontrol, sampel tersebut diambil dengan menggunakan teknik simple random sampling. Hasil analisis univariat menunjukkan subjek pada kelompok kasus sebagian besar (70%) memiliki komorbid dibandingkan dengan kelompok kontrol hanya sedikit memiliki komorbid (23,33%). Nilai OR 7,667 dengan p value 0,000 atau < 0,05 pada analisis bivariat ditemukan pada hubungan komorbid dengan kejadian COVID-19. OR 7,667 menunjukkan bahwa komorbid memiliki hubungan yang signifikan dengan kejadian COVID-19 di Kota Banjarmasin. Kata-kata kunci: komorbid, kejadian, COVID-19

The essential oil from fruit of Syzygium cumini (Myrtaceae), endemic to Indonesia, was investigated by using GC and GC-MS. Forty-six components represented of the total oil were identified. The major components of the essential oil were 1,2,3-Propanetriol (20.32%), octadecanoic acid (16.13%), glycerine-1-oleate-3-palmitate (12.00%), 9,12-Octadecadienoic acid (6.49%) and Heptadecyl acetate (5.52%). The bio-activity of the major components of essential oil of S. cumini was investigated by the PASS-online bio-activity prediction software. The major components of essential oil of S. cumini exhibited antibacterial activities. The antibacterial activity present in the essential oil of S. cumini has the potential to be used as an anti-meningitis bacterial. Further research is needed to test the definitive antibacterial ability of the compounds contained in S. cumini essential oil…