This research is a type of quantitative research with a pre-experimental research design. The purpose of this study was to determine students' mathematics learning outcomes and to determine whether or not there were significant differences before and after the use of powtoon-based learning media. The results showed that there were significant differences before and after learning using Powtoon-based learning media on the Mathematics learning outcomes of fourth grade students of SD Inpres 6/75 Bukaka, Bone Regency. So that Powtoon-based learning media is effective for improving mathematics learning outcomes for fourth grade students at SD Inpres 6/75 Bukaka Bone Regency.

Vaginal discharges are commonly seen in the pediatric population, approximately more than 50% of all pediatric genital complaints. Normal vaginal secretion is usually thin, and clear to white with a variable amount, while malodorous, abnormal consistency of vaginal discharge accompanied by blood, pain, pruritus, or dysuria is usually pathologic. Many factors can cause vaginal discharge such as anatomy of genital area that more susceptible to inflammation and infection, numerous organisms that including those associated with the sexually transmitted diseases or child sexual abuse, also mechanical and chemical substances, as well as poor hygiene. Recurrent vaginal discharge can be very distressing to children, especially if associated with discomfort and the most common cause is vulvovaginitis. The management of vaginal discharge is based on underlying causes, either by initiating proper therapeutic or teaching the children about good hygiene.

Abstrak.Penyakit kusta adalah penyakit yang setua peradaban manusia.telah lama diketahui dan ditulis dalam kitab-kitab kuno. Dalam kitab Sushrat Samhita di zaman India Kuno (1300 SM), tercantum adanya penyakit yang disebut khust dengan deskripsi sesuai dengan kusta serta tulisan pada daun Papyrus di Mesir, tercantum hal mengenai penyakit yang sesuai dengan kusta yang dikenal saat ini. Istilah lepra sendiri berasal dari bahasa Yunani kuno dalam Kitab Perjanjian Baru, merupakan terjemahan dari istilah zaraath dari bahasa Ibrani kuno.Mikobakterium lepra memetabolisme sumber-sumber karbon melalui jalur klasik dari glikolisis, hexose monophosphat shunt dan siklus tricarboxylic acid.Respon yang terjadi akibat infeksi M. Lepra dapat sangat berbeda, keadaan ini terjadi di bawah kontrol secara genetika. Abstract.Abstract Leprosy is a disease that is as old as human civilization. has long been known and written in ancient books. In the book of Sushrat Samhita in Ancient India (1300 BC), there is a disease called khust with description according to the leprosy known today. In the ancient on the leaves of the Papyrus in Egypt,. The term leprosy itself comes from the ancient Greek in the New Testament, a translation of the zaraath term from ancient Hebrew. M.leprae metabolizes carbon sources through the classical pathway of glycolysis, hexose monophosphate shunt and tricarboxylic acid cycles. The response that occurs as a result of Mycobacterium leprae infection can be very different, this situation occurs under genetic control. PendahuluanMorbus Hansen (Lepra, Kusta) adalah infeksi menahun yang disebabkan Mycobacteria leprae (M.lepra) primer yang menyerang saraf tepi, selanjutnya dapat menyerang kulit dan organ lainnya. Penyakit ini dapat mengakibatkan kecacatan jika tidak segera ditatalaksana dan dapat menimbulkan masalah psikososial akibat stigma atau predikat buruk dalam pandangan masyarakat. 1,2,8Strukturn M. lepra Meicobacterium leprae merupakan bakteri yang bersifat obligat intra-seluler (hanya bisa hidup dalam sel) dan dapat bertahan terhadap aksi fagositosis karena mempunyai dinding sel yang sangat kuat dan resisten terhadap aksi lisozim. Mikroskop elektron menunjukkan ultrastruktur yang umum untuk semua mikobakteria. M.leprae berupa batang lurus dengan panjang sekitar 1 sampai 8 µm dan diameter 0,3 µm. Pada jaringan yang terinfeksi batang sering tersusun bersama-sama membentuk globi.

Introduction: Porokeratosis mibelli is a rare, chronic, and slowly progressive genodermatotic characterized by abnormality of keratinization. The clinical manifestations are hyperkeratotic papules or plaques surrounded by a thread-like elevated border that widens centrifugally. Rarity of this case means the science behind it is underdeveloped. Thus, we present this case as an educational vehicle and to further develop the body of knowledge surrounding this disease.Case report: We reported a 3 years old boy, suspect of porokeratosis mibelli. His mother complained of a few reddish spots and patches that sometimes itchy, healed into white and brownish patches with atrophic centers in the last 5 months before admission. Physical examination: few lesions on the back, waist, left side of buttock, back of the neck, and lateral upper left arm. Hypopigmented and hyperpigmented patches with atrophic centers, and erythematous plaques with central erosion were found. No abnormality of internal organs or laboratory findings. Histopathology examination showed epidermis contains of invagination rete malpighia filled keratin. Slightly thinned stratum germinativum with corneum contains basket weave pattern. Topical therapy with 1% 5-fluorourasil cream twice daily showed mild improvement after 10 days.Conclusion: Although clinical examinations of the lesions on this patient did not fit the criteria of porokeratosis mibelli, however, the results of histopathology examination supported the diagnosis. Treatment with 1% 5-fluorourasil cream showed slow but progressive healing on the patient

This study aims to examine the influence of family, economic and lifestyle factors on consumer decisions. This research was conducted at the Royal Spring Housing, located in Gowa Regency. The population chosen is all home consumers at the Royal Spring Housing PT. Buana Sentosa Asri in Makassar. The number of samples is calculated using the Slovin formula, and the number of samples to be studied is 82 household samples and is determined by simple random sampling. Data collection was carried out by distributing questionnaires to all respondents. The analysis tool uses multiple linear regression. The results of the study found that family factors, economic factors, and lifestyle have a positive and significant effect on consumer decisions