A Pd/Ni-free copper-catalysed tandem synthesis was realized for rapid access to unsymmetrical 1,3-diynes from 1,1-dibromoalkenes and terminal alkynes.

A copper-catalyzed tandem protocol using o-hydroxy-gem-(dibromovinyl)benzenes and N-heteroarenes is developed to synthesize a variety of 1-(2-benzofuryl)-N-heteroarenes with a broad substrate scope and high yields.

A one-pot approach with the substrate-driven selective and competitive reactivity of ortho-trifloxy, iodo or bromo functionalized gem-dibromovinylarenes was studied under Pd-catalyzed conditions.