Background: COVID-19 or coronavirus disease 2019 is the unprecedented medical emergency having widespread and multispectral impact. The treatment uncertainty, lack of health infrastructure, lack of available medical professionals, long term implications of COVID-19 are the reasons behind adopting preventive measure over curative measure.  Various preventive measures are available which are tried and tested in previous outbreaks. The measures are reliable and ready to use. Also its efficacy has also been proved. Vaccination drive must be accelerated so as to cover wide section of population as soon as possible. Various preventive measures approved by WHO and various local health authorities are being successfully used in order to gain control over the viral spread. Vaccination which is also a preventive measures has been successfully rolled out in various countries. Conclusion: Vaccine hesitancy is the burning issue which needs to be addresses otherwise it can derail the vaccination efforts. Importance of preventive measure must be highlights time to time. Recent surge in cases in many countries is attribute to the complacent attitude and lax following of preventive guidelines. Many preventive measures are made not only for COVID-19 but it can also protect us from various other contagious diseases and daily allergies of pollution and dust.  Also more innovative mitigation measures should be synthesized in order to contain the viral spread.