Pseudoexfoliation is an inherited microfibrillopathy with public health implication in India, due to its association with age, increased risk of glaucoma and higher incidence of intraoperative (especially difficulty in mydriasis) and postoperative complications of cataract surgery. AIMS: To determine age, sex, Body Mass Index correlation, laterality and intraocular pressure at presentation and effect of mydriasis in patients with pseudoexfoliation. To estimate the prevalence of glaucoma in pseudoexfoliation patients. SETTINGS AND DESIGN: The study is a cross-sectional observation of patients attending the ophthalmology outpatient department at Bhaskar Medical College, Moinabad over a period of 6 months. 38 consecutive patients (and 48 pseudoexfoliative eyes) who fit the inclusion and exclusion criteria were included. METHODS AND MATERIAL: A clinical profile sheet was used to obtain patient information and relevant history of present and past complaints. Recording of height and weight was done, as was visual acuity estimation and examination of anterior segment. Goldman applanation tonometer was used to record intraocular pressure and evaluation of the angle by a four mirror gonioscope. Pupil size was measured before and after the use of 1 drop of 5% w/v phenylephrine and 0.8% w/v tropicamide. RESULTS: Pseudoexfoliation was found to be most common in the 60-69 years age group (55.26%), followed by 70-79 years (21.05%). Males (63.15%) were found to have higher incidence. The majority of patients (68.42%) were found to have Body Mass Index in the range of 18.5-24.9, classified as normal. 73.68% of patients had unilateral presentation. Most pseudoexfoliative eyes (72.91%) showed mydriasis in the range of 6-8 mm. 6.25% patients were diagnosed glaucomatous and 10.41% had ocular hypertension. CONCLUSIONS: 1. Pseudoexfoliation syndrome is an age-related microfibrillopathy, with incidence increasing with age. 2. Males had higher incidence of pseudoexfoliation, consistent with Indian studies. 3. There was no observed higher incidence of pseudoexfoliation in those with lower body mass index. 4. At presentation, pseudoexfoliation syndrome was largely unilateral. 5. Most pseudoexfoliative eyes showed difficulty in mydriasis, consistent with literature. 6. Association of glaucoma and ocular hypertension with pseudoexfoliative eyes was consistent with studies.
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